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NMR A to Z Course. Prof. Gary Martin

NMR A TO Z COURSE (ONLINE) – Professor Gary Martin
December 2, 4 and 6, 2024
11:00-12:00 am (Brasília time)

December 2nd: NMR A to Z presentation

  • Begins with simple 1D 1H and 13C spectral considerations.
  • Progresses to the standard suite of 2D experiments routinely employed (by me anyway) for structure elucidation including COSY, HSQC, HMBC, and HSQC-TOCSY.
  • Introduces the family of ADEQUATE experiments, anisotropic NMR methods, and wraps up with i-HMBC that we developed just over a year ago that differentiated 2JCH from 3JCH HMBC correlations on the basis of sub-ppb (PPB not typo) isotope shifts.

December 4th: Florfenicol – Small Drug Molecule Lecture

  • Walks students through the basic suite of 1D and 2D NMR techniques.
  • Introduces the aspects of multiple halogenation (-Cl and -F) on chemical shift and using heteronuclear JCF coupling as assignment critera.

December 6th: Platensimycin – Complex Natural Product

  • When platensimycin was first isolated and characterized it was necessary to utilize multiple solvent techniques due to proton overlap.
  • Structural characterization using modern techniques including IDR-HSQC-TOCSY, 1,1- and 1,n-ADEQUATE, and i-HMBC will be described.

REGISTRATION

AUREMN Members – FREE
AUREMN Non-members – R$ 300,00

To register, access the link below: https://eventos.galoa.com.br/nmratoz-2024/page/5400-home
Registration period: November 02 to 25, 2024.

More information: sandramello.producoes@gmail.com